Majeed Syndrome – aka Chronic Recurrent Multifocal Osteomyelitis, Congenital Dyserythropoietic Anemia and Neutrophilic Dermatosis Syndrome
Inflammatory Bone Diseases
Autosomal recessive. Two LPIN2 mutations are required to cause symptoms of Majeed.
Currently, the only documented cases of Majeed are of Middle Eastern ancestry. 
Age of onset:
Most present with symptoms in infancy to early childhood, starting between 3 weeks to 2 years of age. 
Neonates: hepatomegaly and neutropenia; anemia is common and can be severe. 
Joints bones muscles cartilage:
Periarticular tender soft tissue swelling. Bone pain. Bone biopsy shows no infection. Early-onset Chronic Recurrent Multifocal Osteomyelitis (CRMO). Periarticular tender soft tissue swelling, short stature, delayed bone age, contractures are often noted. 
Congenital dyserythropoietic anemia (CDA). High ESR. WBC can be normal, or elevated, with neutropenia in infancy. Cultures are negative. 
Majeed Syndrome, Chronic Recurrent Multifocal Osteomyelitis Congenital Dyserythropoietic Anemia and Neutrophilic Dermatosis Syndrome, Inflammatory Bone Diseases, LPIN2, inflammatory dermatosis, Sweet’s syndrome, sweets syndrome, pustular skin lesions, psoriasis, growth delay, hepatomegaly, cholestatic jaundice, bone pain, periarticular, short stature, delayed bone age, Contractures, Chronic Recurrent Multifocal Osteomyelitis, CRMO, Congenital dyserythropoietic anemia, CDA, neutropenia, sweets, sweets syndrome CRMO, sweets bone lesions, soft tissue swelling anemia, soft tissue swelling, anemia, leg pain, stunted growth, large liver, enlarged liver, muscle contractures, pain
Leobarco. Sweet’s syndrome 3 IBDERMA.com Derma Photo gallery by Leobarco, http://www.pbase.com/leobarco/image/69914524
Find periodic fever syndrome panels, which test for Majeed and syndromes with similar symptoms at the same time, at the Genetic Testing Registry (GTR).