PSTPIP1-associated Arthritis, pyoderma gangrenosum and acne (PAPA), aka Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne Syndrome
Currently, the only documented cases are from Europe, New Zealand and the USA. 
Unknown, but rare.
Timing of symptoms:
Early-onset, destructive, recurrent inflammation of the joints, skin and muscle. Flares often occur after mild injury, or injections. 
Pathergy. Pyoderma gangrenosum ulcerative lesions, and/or severe cystic acne. Affected tissues with high neutrophil infiltration. 
Fevers can accompany flares of joint inflammation and pain. Other neurological symptoms are not noted. 
Some patients also have irritable bowel syndrome. 
Joints bones muscles cartilage:
Episodic inflammatory arthritis, often affecting one joint at a time that doesn’t resolve on it’s own. Intermittent sterile pauciarticular, peripheral erosive arthritis. Joint damage and destruction can often develop from the arthritis.     
Not noted. 
Not noted. 
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Pyoderma Gangrenosum, often seen in PAPA - DermAtlas - Dermatology Image Atlas uploaded 9/18/2002. http://dermatlas.med.jhmi.edu/image/pyodermagangrenosum1_020918
Find periodic fever syndrome panels, which test for PAPA and syndromes with similar symptoms at the same time, at the Genetic Testing Registry (GTR).